protein expression

[Scientific Reports] The authors examined the immunohistochemical expression of heme oxygenase-1 in the heart samples to discuss their forensic significance to determine acute cardiac ischemia.

[Molecular Medicine Reports] Researchers explored the role and molecular mechanisms underlying Netrin‑1 in the viability and angiogenic function of EPCs. The apoptosis and various functions of EPCs were analyzed in vitro by manipulating the expression of Netrin‑1.

[Journal of Materials Chemistry B] The authors observed that prostate cancer cells and breast cancer cells cultured with nanodiamonds showed morphological changes and altered gene and protein expression.

[Cell Death & Disease] Scientists showed that ubiquitin specific peptidase 5 (USP5) was a novel PD-L1 deubiquitinase in non-small cell lung cancer (NSCLC) cells. USP5 directly interacted with PD-L1 and deubiquitinated PD-L1, therefore enhances PD-L1 protein stability.

[Cell Biochemistry and Biophysics] Researchers investigated the role of lysocardiolipin acyltransferase expression and activity in mitochondrial oxidative stress, mitochondrial dynamics, and lung epithelial cell apoptosis.

[Circulation Research] Using smooth muscle cells (SMCs), mouse models, and human atherosclerosis specimens, scientists found that focal adhesion kinase (FAK) activation elicited SMC dedifferentiation by stabilizing DNA methyltransferase 3A.