Tag results:
protein expression
Hepatic Cell News
Sulforaphane Ameliorates Non-Alcoholic Fatty Liver Disease in Mice by Promoting FGF21/FGFR1 Signaling Pathway
[Acta Pharmacologica Sinica] Scientists investigated whether fibroblast growth factor 21 (FGF21) was involved in the therapeutic effect of sulforaphane against non-alcoholic fatty liver disease.
Immunology of Infectious Disease News
Lung Epithelial and Endothelial Damage, Loss of Tissue Repair, Inhibition of Fibrinolysis, and Cellular Senescence in Fatal COVID-19
[Science Translational Medicine] Lung autopsy samples from 18 patients with fatal COVID-19, with symptom onset-to-death times ranging from 3 to 47 days, and antemortem plasma samples from 6 of these cases were evaluated using deep sequencing of SARS-CoV-2 RNA, multiplex plasma protein measurements, and pulmonary gene expression and imaging analyses.
Prostate Cell News
Dual Akt and Bcl-2 Inhibition Induces Cell-Type Specific Modulation of Apoptotic and Autophagic Signaling in Castration Resistant Prostate Cancer Cell Lines
[Molecular Biology Reports] The authors elucidated the modulation patterns between apoptosis and autophagy following dual inhibition by Akt inhibitor erufosine and Bcl-2 inhibitor ABT-737 in castration-resistant prostate cancer cell lines, PC-3 (Bax+) and DU-145 (Bax−).
Prostate Cell News
Reorganization of the 3D Genome Pinpoints Non-coding Drivers of Primary Prostate Tumors
[Molecular Medicine Reports] The authors investigated the molecular mechÂÂanisms of long non‑coding RNA small nucleolar RNA host gene 16 in the proliferation and metastasis of prostate cancer cells.
Pulmonary Cell News
CCCTC-Binding Factor Transcriptionally Regulates Galectin-7 and Activates the JNK/STAT3 Axis to Aggravate Bronchial Epithelial Cell Injury
[Pediatric Pulmonology] Human bronchial epithelial cells BEAS-2B were stimulated with transforming growth factor-β1 at a concentration of 10 ng/mL, and CCCTC-binding factor (CTCF) overexpression plasmid and CTCF small interfering RNA were transfected into the cells.
Mammary Cell News
Fluid Flow Exposure Promotes Epithelial-to-Mesenchymal Transition and Adhesion of Breast Cancer Cells to Endothelial Cells
[Breast Cancer Research] Researchers showed that fluid forces on the order of 1 Pa promoted epithelial-to-mesenchymal transition and adhesion of breast cancer cells to an endothelial monolayer and identified biomarkers were distinctly expressed in patient populations.