[Cell Biochemistry and Biophysics] Researchers investigated the role of lysocardiolipin acyltransferase expression and activity in mitochondrial oxidative stress, mitochondrial dynamics, and lung epithelial cell apoptosis.
[Cell Death & Disease] Researchers found that telomerase reverse transcriptase (TERT) was significantly reduced in lung tissue of Nrf2−/− mice in the model of intestinal ischemia/reperfusion-induced acute lung injury (IIR-ALI)
[Cell Reports] The ABL tyrosine kinases promote metastasis, and enhanced ABL signaling is associated with a poor prognosis in lung adenocarcinoma patients. Researchers showed that ABL kinase allosteric inhibitors impaired mitochondrial integrity and decrease oxidative phosphorylation.
[Acta Histochemica] Researchers identified the morphological characteristics of the neuroendocrine phenotype in a human lung cancer cell line, induced by two cAMP elevating agents.
[Scientific Reports] Researchers investigated whether electroporation-mediated gene transfer of MRCKα to the lungs can attenuate LPS-induced acute lung injury in vivo.
[Scientific Reports] Researchers investigated the role of mTORC1 in regulating translationally controlled tumor protein levels, thereby modulating chemosensitivity, in human lung cancer cells and an A549 lung cancer xenograft model.