reporter assay

[Scientific Reports] Investigators showed that the long-noncoding RNA colorectal neoplasia differentially expressed (CRNDE) was overexpressed in both acute myeloid leukemia samples and cell lines. CRNDE silencing inhibited proliferation and increased apoptotic rate and cell cycle arrest of KG-1a cells.

[Laboratory Investigation] Scientists explored the underlying mechanism of metastasis-associated lung adenocarcinoma transcript 1 (MALAT1)-regulated angiogenesis during bone regeneration.

[Cell Death & Disease] Scientists identified APOL1 was abnormally elevated in human pancreatic cancer tissues compared with that in adjacent tissues and was associated with poor prognosis.

[Histology and Histopathology] Scientists used NSCLC tissues, as well as cell lines to elucidate the expression and location of circRIP2 in NSCLC. They also established the circRIP2 overexpression cells A549-circRIP2 and repression cells HCC827-shcircRIP2 for further functional and mechanism studies.

[Cell Biology International] Cardiac function, myocardial infarction area, apoptosis, and angiogenesis were all evaluated in a CHF rat model following treatment with human umbilical cord MSC-derived exosomes.

[Oncology Reports] Investigators investigated the inhibitory effect of miR‑367‑3p on the proliferation, invasion, and metastasis of prostate cancer cells.