reporter assay

[Inflammation Research] miR-342-3p overexpression in LCSC lead to lower tumor volume, reduced tumor spheroid formation and agar colony formation rates, as well as lower mRNA and protein expressions of CD44, ALDH1, Bmi1, Sox2, and Oct4.

[Molecular Medicine Reports] The authors explored the role and molecular mechanism of lncRNA small nucleolar RNA host gene 1 (SNHG1) in ischemic cardiomyocyte injury.

[Journal of Nanobiotechnology] Investigators explored the effects of extracellular vesicles from human hypoxic olfactory mucosa MSCs on angiogenesis and its underlying mechanism.

[Cancer Gene Therapy] Investigators uncovered that the transcription factor p53 could upregulate miR-519d-3p expression to directly suppress the expression of E2F transcription factor 1 (E2F1), thus inhibiting prostate cancer growth and metastasis.

[Bioengineered] Scientists investigated the specific impacts of umbilical cord mesenchymal stem cells overexpressing miR-455-5p in intrauterine adhesions.

[Cell Death Discovery] Accumulating evidence revealed that long noncoding RNAs (lncRNAs) have been participating in cancer malignant progression, including glioblastoma multiforme (GBM). Scientists illuminated the definite mechanism of HNF1A-AS1 in promoting GBM malignancy.