rheumatoid arthritis

[Experimental & Molecular Medicine] Scientists suggested that inflammatory mediators in synovial fluid, including TNF-α, recruited sodium bicarbonate cotransporter n1 (NBCn1) to the plasma membrane of fibroblast-like synoviocytes to provide dynamic properties and that modulation of NBCn1 could be developed into a therapeutic strategy for rheumatoid arthritis.

[Experimental & Molecular Medicine] Scientists suggested that inflammatory mediators in synovial fluid, including TNF-α, recruited sodium bicarbonate cotransporter n1 (NBCn1) to the plasma membrane of fibroblast-like synoviocytes to provide dynamic properties and that modulation of NBCn1 could be developed into a therapeutic strategy for rheumatoid arthritis.

[International Journal of Urology] Further study into the “Gut–Prostate Axis” would help in the discovery of new strategies for the prevention, screening, and treatment of prostate cancer.

[Stem Cell Research & Therapy] The authors performed a Phase I/IIa non-randomized, open-label study to evaluate the safety and efficacy of a single, intravenous infusion of autologous, adipose-derived MSCs over a period of 52 weeks, in patients with active rheumatoid arthritis.

[Proceedings of the National Academy of Sciences of the United States of America] Usp38−/− mice were more susceptible to inflammatory damage and death and developed more serious pulmonary fibrosis after bleomycin treatment.

[Scientific Reports] Murine splenocytes were differentiated into T helper 17 cells, and the effect of the TGF-βRI inhibitor SB-505124 was studied.