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SARS-CoV-2

Clinical and Virological Characteristics of SARS-CoV-2 B.1.617.2 (Delta) Variant: A Prospective Cohort Study

[Clinical infectious Diseases] COVID-19 patients infected with the delta variant exhibited prolonged viable viral shedding with more severe symptoms than those infected with non-delta variants.

Poly(I:C) Enhances Mesenchymal Stem Cell Control of Myeloid Cells From COVID-19 Patients

[iScience] The authors hypothesized that viral mimic-priming improved mesnchymal stem cells' abilities to rebalance the dysregulated immune responses in COVID-19.

Absence of SARS-CoV-2 Spike Glycoprotein Expression in Placentas from Individuals after mRNA SARS-CoV-2 Vaccination

[Modern Pathology] Scientists identified 48 patients receiving one or two doses of mRNA SARS-CoV-2 vaccine during gestation and used immunohistochemistry against SARS-CoV-2 Spike protein in formalin-fixed, paraffin-embedded placental tissue.

Neuropathology and Virus in Brain of SARS-CoV-2 Infected Non-Human Primates

[Nature Communications] Scientists showed that neuroinflammation, microhemorrhages, brain hypoxia, and neuropathology that is consistent with hypoxic-ischemic injury in SARS-CoV-2 infected non-human primates, including evidence of neuron degeneration and apoptosis.

Human Liver Organoid Derived Intra-hepatic Bile Duct Cells Support SARS-CoV-2 Infection and Replication

[Scientific Reports] Researchers studied that intra-hepatic bile duct cells could be grown using a human liver organoid platform.

Ultrastructural Insight into SARS-CoV-2 Entry and Budding in Human Airway Epithelium

[Nature Communications] Investigators examined human airway epithelium infected with three different isolates of SARS-CoV-2 including the B.1.1.7 variant by transmission electron microscopy and tomography.

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