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smooth muscle cells

Baicalin Alleviates Thrombin-Induced Inflammation in Vascular Smooth Muscle Cells

[Biomed Research International] Researchers investigated the capacity for thrombin to trigger inflammation and induce cell proliferation in vascular smooth muscle cells.

Ubiquitinated AIF Is a Major Mediator of Hypoxia-Induced Mitochondrial Dysfunction and Pulmonary Artery Smooth Muscle Cell Proliferation

[Cell & Bioscience] Scientists investigated the specific involvement of apoptosis-inducing factor, a mitochondrial oxidoreductase in regulating mitochondrial energy metabolism and mitophagy in pulmonary artery smooth muscle cells.

Microskeletal Stiffness Promotes Aortic Aneurysm by Sustaining Pathological Vascular Smooth Muscle Cell Mechanosensation via Piezo1

[Nature Communications] Scientists showed defective mechano-phenotype signatures of vascular smooth muscle cells in abdominal aortic aneurysms measured with ultrasound tweezers-based micromechanical system and single-cell RNA sequencing technique.

Upregulation of TGF-β Type II Receptor in High Glucose-Induced Vascular Smooth Muscle Cells

[Molecular Biology Reports] Scientists investigated the effects of high-glucose conditions on TGF-β type II receptor expression levels, cell viability, and migration rate in vascular smooth muscle cells.

Phosphodiesterase 4D Promotes Angiotensin II-Induced Hypertension in Mice via Smooth Muscle Cell Contraction

[Communications Biology] Researchers revealed that phosphodiesterase (PDE) 4D expression was upregulated in the aortas of experimental hypertension induced by angiotensin II.

The MFF-SIRT1/3 Axis, Regulated by miR-340-5p, Restores Mitochondrial Homeostasis of Hypoxia-Induced Pulmonary Artery Smooth Muscle Cells

[Laboratory Investigation] Pulmonary artery smooth muscle cells were cultured in hypoxia condition for constructing a pulmonary arterial hypertension model in vitro. The expression of genes and proteins were determined by qRT-PCR and western bolt assays.

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