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squamous cell carcinoma

The Landscape of Driver Mutations in Cutaneous Squamous Cell Carcinoma

[NPJ Genomic Medicine] Researchers provided a catalog of driver genes in cutaneous squamous cell carcinoma, offering points of therapeutic intervention and insights into the biology of cutaneous squamous cell carcinoma.

FGFR2 Maintains Cancer Cell Differentiation via AKT Signaling in Esophageal Squamous Cell Carcinoma

[Cancer Biology & Therapy] Scientists showed that fibroblast growth factor receptor 2 (FGFR2), particularly the IIIb isoform, was highly expressed in non-CSCs.

FDA Approves Pembrolizumab for Locally Advanced Cutaneous Squamous Cell Carcinoma

[OncLive, Inc.] The FDA has expanded the label for pembrolizumab for use as a monotherapy in the treatment of patients with locally advanced cutaneous squamous cell carcinoma that was not curable by surgery or radiation.

Molecular Pathology of Skin Adnexal Tumors

[Histopathology] Investigators provide a comprehensive overview and update of the molecular findings associated with adnexal tumors of the skin.

lncRNA HCP5 Acts as a ceRNA to Regulate EZH2 by Sponging miR-138-5p in Cutaneous Squamous Cell Carcinoma

[International Journal of Oncology] Researchers examined the competing endogenous RNA network in cutaneous squamous cell carcinoma.

Bristol Myers Squibb Receives Positive CHMP Opinion for Opdivo (Nivolumab) as Adjuvant Treatment for Esophageal or Gastroesophageal Junction Cancer Patients with Residual Pathologic Disease...

[Bristol Myers Squibb] Bristol Myers Squibb announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency has recommended approval of Opdivo for the adjuvant treatment of adult patients with esophageal or gastroesophageal junction cancer who have residual pathologic disease following prior neoadjuvant chemoradiotherapy

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