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squamous cell carcinoma

The Potential Role of miR-1290 in Cancer Progression, Diagnosis, Prognosis, and Treatment: An oncomiR or Onco-Suppressor microRNA?

[Journal of Cellular Biochemistry] MiR-1290 was discovered for the first time in human embryonic stem cells, and under typical physiological situations, plays an essential role in neuronal differentiation and neural stem cell proliferation.

Zinc-Finger Protein 750 Mitigates Malignant Biological Behavior of Oral CSC-Like Cells Enriched from Parental CAL-27 Cells

[Oncology Let] Scientists elucidated the role of ZNF750 in the inhibition of the renewal ability of CSCs derived from the oral squamous cell carcinoma cell line, CAL‑27.

A Tumor-Derived Type III Collagen-Rich ECM Niche Regulates Tumor Cell Dormancy

[Nature Cancer] Investigators studied how disseminated tumor cells sensed and remodeled the ECM to sustain dormancy.

SOTIO Announces Clinical Collaboration with MSD to Evaluate IL-15 Superagonist, SOT101, in Combination with KEYTRUDA® (Pembrolizumab) in Patients with Solid Tumors

[SOTIO Biotech] SOTIO Biotech announced that it has entered into a clinical trial collaboration and supply agreement with MSD to evaluate the combination of SOT101, SOTIO’s IL-15 superagonist, and MSD’s KEYTRUDA® in patients with selected advanced/refractory solid tumors in the Phase II AURELIO-04 study.

RNF168 Suppresses the Cancer Stem Cell-Like Traits of Nonsmall Cell Lung Cancer Cells by Mediating RhoC Ubiquitination

[Environmental Toxicology] Researchers found that RNF168 expression was positively correlated with the overall survival, first-progression survival, and postprogression survival of lung adenocarcinoma, but not correlated with these survivals of squamous cell carcinoma of lung.

The Potential of Gene Therapy for Recessive Dystrophic Epidermolysis Bullosa

[British Journal of Dermatology] Investigators explain the principles of different approaches of gene therapy, summarize its journey and discuss its current and future impact in recessive dystrophic epidermolysis bullosa.

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