survivin

[Journal of Experimental & Clinical Cancer Research] Investigators generated organoids from circulating tumor cells isolated from an orthotopic colorectal cancer xenograft model.

[Biochemical and Biophysical Research Communications] Scientists found that the expression level of YAP/TAZ in tamoxifen-resistant MCF7 breast cancer cells was significantly increased compared with that in MCF7 cells.

[IMV Inc.] IMV, Inc., a clinical-stage company developing a portfolio of immune-educating therapies based on its novel DPX platform to treat solid and hematologic cancers, announced a first patient dosed in the VITALIZE Phase IIB clinical trial.

[Journal of Materials Chemistry B] The authors found that the inhibition of Hsp90 could inhibit the overexpression of its client proteins such as anti-apoptotic proteins and androgen receptor, thereby improving the efficacy of photodynamic therapy and inducing prostate cancer cell apoptosis.

[Radiation Research] Investigators demonstrated that STAT3 blockade with a STAT3 inhibitor or siRNA increased the radiosensitivity of prostate cancer (PCa) cells and that radiation together with STAT3 blockade induced more apoptosis and double-strand breaks than radiation alone in LNCaP cells.

[Heliyon] Researchers suggested that galactosylated nanoliposomes incorporating ARV-825 was a novel actively targeted PROTAC-based nanotherapeutic approach for hepatocellular carcinoma.