TNF-α

[Journal of Biological Chemistry] Scientists showed that cellular communication of exosomal TNF-α from Huh-7 regulatesdosteoclast differentiation through NF-κB/CTSK/TRAP expressions.

[Scientific Reports] Researchers explored the roles and related mechanisms of lncRNA-TCONS_00147848 in nasal mucosa cell apoptosis and allergic rhinitis (AR). AR mice were sensitized with ovalbumin, with the TCONS_00147848 interference lentiviral vector and FOSL2 overexpressing lentiviral vectors constructed respectively.

[Scientific Reports] Human umbilical vascular endothelial cells were cultured with or without COL-4A1 and TNF-α. Cell Counting Kit-8, wound-healing, Transwell and tube formation assays were used to evaluate cell proliferation, migration and angiopoiesis.

[PLOS Neglected Tropical Diseases] A model of HTLV-1 and S. stercoralis coinfection in CD34+ umbilical cord blood hematopoietic stem cell engrafted humanized mice was established.

[Immunopharmacology and Immunotoxicology] Scientists determined the effects of indoximod as an indoleamine 2,3-dioxygenase inhibitor on triple-negative breast cancer and to assess the link between the efficacy of indoximod and IFN-γ or TNF-α stimulation.

[Scientific Reports] Researchers investigated the comprehensive cytokine dynamics following endoscopic submucosal dissection in patients with oesophageal cancer.