Publication

[Nature Immunology] As liver tissue-resident memory T cells (Trm cells) have recently been shown to control liver-stage infections, scientists embarked on a mRNA-based vaccine strategy to induce liver Trm cells to prevent malaria.

[Nature Communications] Researchers characterized a new type of proteinuria originating as part of a viral response. Inoculation of SARS-CoV-2 caused increased soluble urokinase receptor (suPAR) levels and glomerulopathy in African green monkeys.

[Proceedings Of The National Academy Of Sciences Of The United States Of America] The authors described a mechanism of restriction against human T cell leukemia virus type 1 by the helicase-like transcription factor.

[Cell Reports] Researchers examined the role of the adaptive immune response in adipose tissue wasting and cachexia using a murine model of the chronic parasitic infection Trypanosoma brucei.

[Cellular and Molecular Life Sciences] Investigators elucidated the mechanisms underlying the suppressive effect exerted by MDSC on CD4+ T cells during chronic S. aureus infection.

[Nature Biotechnology] To investigate whether healthy glia can outcompete diseased human glia in the adult forebrain, scientists engrafted wild-type human glial progenitor cells (hGPCs) produced from human embryonic stem cells into the striata of adult mice that had been neonatally chimerized with mutant Huntingtin-expressing hGPCs.