Publication

[International Immunopharmacology] Investigators constructed a T-cell epitope-rich tripeptide-splicing fragment of Rv2201 from the Mycobacterium tuberculosis genome, ultimately yielding the recombinant protein Rv2201-519 in Escherichia coli BL21.

[Journal Of Infectious Diseases] Six people with HIV received infusions of 2 × 107 HIV-specific T cells/m² with vorinostat 400 mg, and 3 eople with HIV received infusions of 10 × 107 HIV-specific T cells/m² with vorinostat. The frequency of persistent HIV by multiple assays including quantitative viral outgrowth assay of resting CD4+ T cells was measured before and after study therapy.

[New Phytologist] Scientists highlighted the significance of poplar MYC2s and terpenes in mutualistic symbiosis by controlling root fungal colonization. They identified poplar genes in which direct or indirect control by MYC2 is required for ECM establishment.

[npj Parkinson's Disease] Researchers investigated the electrophysiological properties, synaptic activity, and gene expression differences in dopaminergic neurons derived from iPSCs of healthy controls, sporadic Parkinson's disease (PD) patients, and PD patients with E326K-GBA1 mutations.

[Aging] The authors examined how Dickkopf-1 (DKK1) expression varied across different tumor and normal tissues. They investigated the association between DKK1 mRNA expression and clinical outcomes.

[Bone Marrow Transplantation] Researchers examined vaccine responses in relation to immune reconstitution and post hematopoietic cell transplantation (HCT) rituximab administration. Their single center retrospective study included 251 patients with hematological malignancies who received a CD34-selected HCT.