Publication

[ACS Nano] To investigate whether black phosphorus nanosheets have positive bio-effects on in situ skin repair, the authors verified black phosphorus nanosheets’ positive effects on angiogenic and anti-inflammatory abilities in vitro.

[BMC Medicine] Scientists presented a computational model, pyroptosis-related gene score, or PScore, to assess pyroptosis status. They applied PScore to 1388 melanoma samples in amn in-house cohort and eight other publicly available independent cohorts.

[Nature Communications] Using genome editing in human stem cells, scientists showed that beta cells lacking SOX9 had stunted first-phase insulin secretion.

[Molecular Metabolism] Using patient-derived iPSCs and mutated hESCs, researchers detected accumulation of misfolded proinsulin and impaired proinsulin processing in vitro, and a dominant-negative effect of these mutations on beta-cell mass and function after transplantation into mice.

[Developmental Cell] Investigators identified cellular rearrangements between acinar and ductal progenitors as a mechanism to drive branching morphogenesis in the pancreas while preserving the integrity of the acinar-ductal functional unit.

[Scientific Reports] Researchers investigated the effects of the two ANO1-inhibitors niclosamide and benzbromarone in vitro and in vivo in mouse models for cystic fibrosis and asthma.