Publication

[Advanced Science] Using MRL/lpr lupus mice and a nephrotoxic serum-induced lupus nephritis model, investigators demonstrated that group 3 innate lymphoid cells accumulated in the kidney migrated predominantly from the intestine.

[International Journal of Cancer] Scientists investigated the suitability of the Cyclin K-CDK12 complex as a novel therapeutic approach in prostate cancer using the new covalent CDK12/13 inhibitor THZ531.

[Cancer Cell International] The authors confirmed that Glutamate decarboxylase 1 (GAD1) was a hub gene in the progression and development of drug resistance in prostate cancer.

[Molecular Cancer Research] Transcriptome profiling in androgen receptor-positive prostate cancer cells revealed that nuclear mTOR generally downregulated a subset of the androgen response pathway independently of its kinase activity.

[Biochemical Pharmacology] Forkhead box (FOX) S1 knockdown inhibited prostate cancer cell proliferation, invasion, migration, EMT and tumor growth while increased cell apoptosis.

[Environmental Toxicology] Researchers delved at how the natural substance dieckol prevented prostate cancerous cells from proliferating and migrating by blocking the JAK/STAT3 signaling pathway in PC-3 cells.