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Exploring the Crosstalk between Endothelial Cells, Immune Cells, and Immune Checkpoints in the Tumor Microenvironment: New Insights and Therapeutic Implications

[Cell Death & Disease] The authors elucidate the relationship between endothelial cells, immune cells, and immune checkpoints in the tumor microenvironment , with the ultimate goal of identifying novel therapeutic targets and charting new avenues for immunotherapy.

Engineering Biomaterials to Tailor the Microenvironment for Macrophage–Endothelium Interactions

[Nature Reviews Materials] Scientists summarize studies using biomaterials as extracellular matrix with tenable properties to manipulate macrophage–endothelial cell fate to regulate innate and adaptive immunity, angiogenesis and regeneration.

Hemostasis Without Clot Formation – How Platelets Guard the Vasculature in Inflammation, Infection, and Malignancy

[Blood] The authors summarize previously recognized and more recent studies that have elucidated how anucleate, small platelets manage to maintain vascular integrity when faced with challenges of infection, sterile inflammation and even malignancy. They dissect how platelets are recruited to the vascular wall, how they identify sites of injury, and how they prevent hemorrhage as single cells.

Bronchial Epithelial and Airway Smooth Muscle Cell Interactions in Health and Disease

[Heliyon] The author summarizes the growing evidence of bronchial epithelial cells and airway smooth muscle cells crosstalk under normal and pathophysiological conditions, first discussing the impact of airway smooth muscle cells on the epithelium in inflammatory settings.

The Skin Barrier: An Extraordinary Interface With an Exceptional Lipid Organization

[Progress in Lipid Research] The authors provide a historical overview of the steps undertaken to obtain information on the lipid composition and organization in stratum corneum of healthy skin and inflammatory skin disease.

Cellular Stress in the Pathogenesis of Nonalcoholic Steatohepatitis and Liver Fibrosis

[Nature Reviews Gastroenterology & Hepatology] The authors provide an overview of studies that analyze the role of cellular stress in different cell types involved in fibrogenesis, including hepatocytes, hepatic stellate cells, liver sinusoidal endothelial cells and macrophages.

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