Review

[Trends in Cell Biology] Endothelial cells acquire mitochondria via tunneling nanotubes and extracellular vesicles, enhancing resilience under stress and promoting vascular repair.

[Nature Reviews Cardiology] Investigators describe the rationale for gene therapy to treat cardiac arrhythmias and discuss advantages and disadvantages of gene silencing, gene replacement, gene suppression-and-replacement and gene editing technologies.

[Circulation Research] Exercise enhances metabolic health by promoting muscle growth, mitochondrial biogenesis, and improved nutrient storage while preventing age-related muscle dysfunction.

[Molecular Cancer] Researchers explore recent advances in understanding how niche factors regulate cell fate determination between skin stem cells and skin cancer stem cells, along with their clinical implications.

[Nature Reviews Urology] Immunotherapy, targeted therapy and gene therapy could have reciprocal synergistic effects in prostate cancer in combination, resulting in a proposed synergistic model encompassing these three therapeutic modalities, presenting novel potential treatment strategies for prostate cancer.

[Trends in Cancer] Scientists discuss how early driver mutations and epigenetic alterations contribute to the establishment of an immunosuppressive microenvironment in colorectal cancer