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Annals of the Rheumatic Diseases Collection on Autoantibodies in the Rheumatic Diseases: New Insights into Pathogenesis and the Development of Novel Biomarkers

[Annals Of The Rheumatic Diseases] While autoantibodies have been investigated for over 50 years, recent studies have provided an exciting perspective on the mechanisms of autoantibody production and the power of new technologies to identify novel autoantibody targets to elucidate aetiology and underpin patient evaluation.

Immune Regulatory Networks Coordinated by Glycans and Glycan-Binding Proteins in Autoimmunity and Infection

[Cellular & Molecular Immunology] The authors review the spatiotemporal regulation of selected glycan-modifying processes including mannosylation, complex N-glycan branching, core 2 O-glycan elongation, LacNAc extension, as well as terminal sialylation and fucosylation.

The Role of Candidate Transport Proteins in Beta Cell Long-Chain Fatty Acid Uptake: Where Are We Now?

[Diabetic Medicine] Scientists detail more than 40 years of literature investigating the role of membrane-associated transport proteins in long-chain free fatty acids uptake. By focusing on what is known in other cell types, we highlight where we can extrapolate our current understanding of protein-mediated transport to beta cells and uncover where further understanding is required.

Cell Transplantation-Based Regenerative Medicine in Liver Diseases

[Stem Cell Reports] The authors evaluate the current preclinical state of liver bioengineering, the clinical context for liver cell therapies, the cell sources, the delivery routes, and the results of clinical trials for end-stage liver disease.

Melanoma-Derived Mediators Can Foster the Premetastatic Niche: Crossroad to Lymphatic Metastasis

[Trends In Immunology] The authors discuss tumor secretory factors involved in subverting tumor immunity and remodeling lymph nodes and highlight emerging therapeutic strategies.

Maturation of a Postsynaptic Domain: Role of Small Rho GTPases in Organizing Nicotinic Acetylcholine Receptor Aggregates at the Vertebrate Neuromuscular Junction

[Journal of Anatomy] The authors integrate evidence of key processes and molecules that have shed light on their current understanding of the neuromuscular junction maturation process.

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