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Epigenetic Regulation in the Tumor Microenvironment: Molecular Mechanisms and Therapeutic Targets

[Signal Transduction and Targeted Therapy] Investigators present an up-to-date and thorough description of how epigenetic modifications in tumor cells influence immune cell responses in the tumor microenvironment.

Telomerase-Targeted Therapies in Myeloid Malignancies

[Blood Advances] The authors summarize telomere and telomerase biology as it relates to both physiologic and malignant cells. They discuss the development of telomere and telomerase targeted therapeutic candidates within the realm of myeloid malignancies.

The Role of m6A mRNA Modification in Normal and Malignant Hematopoiesis

[Journal of Leukocyte Biology] Investigators focus on recent progress in identifying the biological functions of m6A mRNA modification, its regulators, and downstream gene targets during normal and pathological hematopoiesis.

Research Progress on the Hematopoietic Microenvironment in Aplastic Anemia

[European Journal of Haematology] Scientists summarize the research on the hematopoietic microenvironment of aplastic anemia (AA) in recent years to provide new ideas for the clinical treatment of AA.

Lessons and Gaps in the Prediction and Prevention of Type 1 Diabetes

[Pharmacological Research] The authors review key knowledge related to the prediction and prevention of type 1 diabetes in youth, with a focus on both pharmacological and non-pharmacological prevention.

Assembling the Puzzle Pieces: Insights for in Vitro Bone Remodeling

[Stem Cell Reviews And Reports] The authors describe osteoblastogenesis and osteoclastogenesis as two vital processes for producing mature, active bone cells in the context of interactions between cells and the bone matrix.

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