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Gene Expression in Organoids: An Expanding Horizon

[Biology Direct] The authors review current state-of-the-art multi-omics technologies, such as single-cell transcriptomics and chromatin accessibility assays, employed to study organoids as a model for development and a platform for precision medicine.

Functionalization of Curcumin Nanomedicines: A Recent Promising Adaptation to Maximize Pharmacokinetic Profile, Specific Cell Internalization, and Anticancer Efficacy against Breast Cancer

[Journal of Nanobiotechnology] The authors ponder the biomedical significance of various curcumin (Cur)-nanomedicines and adaptable functionalizations for amplifying the physicochemical properties and anticancer efficacy of the Cur while reversing the multidrug resistance and reoccurrence in breast cancer.

The Metabolic Landscape of Breast Cancer and Its Therapeutic Implications

[Molecular Diagnosis & Therapy] Scientists illustrate the altered metabolism in breast cancer and its underlying mechanisms, as well as metabolic interventions in breast cancer treatment, with the intention to provide strategies for developing novel therapeutic treatments for breast cancer.

Calcium Signaling Pathways in Prostate Cancer Initiation and Progression

[Nature Reviews Urology] The authors summarize preclinical and clinical evidence suggesting that altered calcium signaling is a crucial component of the molecular re-programming that drives prostate cancer progression.

Impact of the Source of Hematopoietic Stem Cells on Immune Reconstitution after Transplantation: A Systematic Review

[European Journal Of Haematology] Scientists analyze the kinetic of immune reconstitution among umbilical cord blood, peripheral blood, and bone marrow in hematopoietic stem cell transplant patients by focusing on natural killer cells, B and T lymphocytes, and neutrophils.

The Potential of miR-21 in Stem Cell Differentiation and Its Application in Tissue Engineering and Regenerative Medicine

[Stem Cell Reviews and Reports] The authors discuss the function of miR-21 in regenerative medicine of the liver, nerve, spinal cord, wound, bone, and dental tissues. In addition, the function of natural compounds and lncRNAs was analyzed as potential regulators of miR-21 expression in regenerative medicine.

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