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Review

LCN2: Versatile Players in Breast Cancer

[Biomedicine & Pharmacotherapy] The authors in-depth review of the advancement of Lipocalin 2 (LCN2) in the context of breast cancer occurrence and development.

Breaking the Mold With RNA—A “RNAissance” of Life Science

[NPJ Genomic Medicine] Investigators provide a forward-looking perspective on the field of RNA medical products and the potential long-term innovations and policy shifts enabled by this revolutionary and game-changing technological platform.

Resveratrol and p53: How Are They Involved in CRC Plasticity and Apoptosis?

[Journal of Advanced Research] Investigators summarize the latest published research on resveratrol’s effect in the prevention of CRC, its regulatory actions, specifically on the p53 pathway, and its treatment options.

Neocortical Neurogenesis in Development and Evolution—Human-Specific Features

[Journal of Comparative Neurology] The authors review the ability of ARHGAP11B to amplify basal progenitors and to expand a primate neocortex and discuss the contribution of ARHGAP11B to neocortex expansion during human evolution.

Myeloid-Derived Suppressor Cells in Cancer and Cancer Therapy

[Nature Reviews Clinical Oncology] The authors discuss the interplay between myeloid-derived suppressor cells (MDSCs) and various other cell types found in tumors as well as the mechanisms by which MDSCs promote tumor progression.

Novel Signatures of Prostate Cancer Progression and Therapeutic Resistance

[Expert Opinion On Therapeutic Targets] The authors review the role of different molecular determinants of prostate cancer progression to lethal disease including the phenotypic dynamic of cell plasticity, EMT-MET interconversion, and signaling-pathways driving prostate cancer cells to advance and metastasize.

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