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NIH Pay Raise for Postdocs and PhD Students Could Have US Ripple Effect

[Nature News] The US National Institutes of Health (NIH) said it will raise the salaries of thousands of postdoctoral researchers and graduate students who receive a prestigious NIH research fellowship. The move could boost pay for other scientists as well, because academic institutions often follow guidelines set by the NIH.

In a Scientific First, Researchers Use CRISPR Base Editing to Treat Liver Disease in Fetal Monkeys

[STAT News] Scientists reported on Monday, April 22 that they used a form of the technology known as “base editing” to alter the DNA of laboratory monkeys in the womb, substantially reducing the levels of a toxic protein that causes a fatal liver disease before the animals had even been born.

Dr. Ashley Nelson Receives Hartwell Foundation Individual Biomedical Research Award

[Weill Cornell Medicine] Dr. Ashley Nelson has received a 2023 Hartwell Individual Biomedical Research Award from The Hartwell Foundation. The award provides $100,000 direct cost support per year for three years and designation as a Hartwell Investigator.

Evexta Bio Reports Progress towards Clinical Development of Rupitasertib in Advanced Breast Cancer

[Evexta Bio SA] Evexta Bio SA provided an update on the clinical development of its lead asset, rupitasertib, a selective oral inhibitor of S6K and AKT1/AKT3.

Palisade Bio Successfully Demonstrates Bioactivation of PALI-2108 in Ex-Vivo Study of Normal Healthy and Ulcerative Colitis Patients’ Stool

[Palisade Bio, Inc.] Palisade Bio, Inc. announced the successful completion of its analysis evaluating ex-vivo bioactivation of PALI-2108, an orally administered, locally acting colon-specific phosphodiesterase-4 (PDE4) inhibitor prodrug in development for patients affected by ulcerative colitis.

UCSF Launches Clinical Trial on New CAR T Therapy for Glioblastoma

[Insider Precision Medicine] Researchers at the University of California, San Francisco (UCSF) have begun enrollment for a clinical trial that uses a new, powerful version of CAR T as a potential therapy for glioblastoma, the most common and deadly adult brain cancer.

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