Publication

[International Journal Of Cancer] The authors investigated the molecular mechanism through which ERα/LKB1 complex might modulate the expression of E-cadherin, influencing tumor growth, progression, and distant metastasis.

[Cell Death Discovery] Multiomics analysis of chromatin immunoprecipitation sequencing and RNA sequencing were performed in cell lines derived from endometrial cancer and mammary tumor to screen the differential co-regulatory factors of progesterone receptor.

[Molecular Carcinogenesis] Scientists identified a deubiquitinase, ubiquitin-specific peptidase 9, X-linked (USP9X), that could physically interact with and deubiquitinate K48-linked ubiquitinated cell division cycle 123 (CDC123) at the K308 site.

[Cell Communication And Signaling] PIP5Kα, Merlin, or LATS1 knockout or knockdown cells and transfected cells with them were used. LATS1, YAP, and TAZ activities were measured using biochemical methods and PIP2 levels were evaluated using cell imaging.

[Oncology Letters] The use of a convolutional neural network‑based artificial intelligence for circulating tumor cells detection was assessed using KYSE esophageal squamous cell carcinoma (ESCC) cell lines and blood samples from patients with ESCC.

[Cellular Signalling] The authors identified epigenetic modifications involved in the control of the Wnt/β-catenin signaling and investigate the role of this pathway in the accumulation of CSC and chemoresistance of Head and Neck Squamous Cell Carcinoma.