Publication

[Nature Communications] Using combined approaches, including scRNA-seq, researchers confirmed that autophagy-related gene 5 deletion interrupted developmental temporal order of endothelial to hematopoietic transition to further affect the pre-HSC I maturation.

[Cellular and Molecular Life Sciences] Researchers revealed the novel functions of mouse Txnip in cellular reprogramming and differentiation onset by involving in glucose-mediated histone acetylation and the regulation of Oct4, which was a fundamental component of the molecular circuitry underlying pluripotency.

[Molecular Psychiatry] Scientists reported that Scn2a-deficient mice had impaired learning and memory, accompanied by reduced synaptic transmission and lower spine density in neurons of the hippocampus.

[Cell Reports] Scientists reported that YTHDF1 was highly expressed in allergic airway epithelial cells and asthmatic patients and that it influenced proinflammatory responses.

[Cancer Biology & Therapy] The authors investigated the role of carnitine palmitoyltransferase 1A (CPT1A), which was a succinyltransferase in the progression of prostate cancer. CCK-8 was used to detect the cell viability.

[Proceedings Of The National Academy Of Sciences Of The United States Of America] Dog models of multiple sclerosis received either a single treatment of stem cells or a single treatment of exosomes intrathecally and the treatment process was evaluated clinically, radiologically, histopathologically, and electron microscopy and cerebrospinal fluid analysis.