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Muscle Cell News
LSD1 Controls a Nuclear Checkpoint in Wnt/β-Catenin Signaling to Regulate Muscle Stem Cell Self-Renewal
[Nucleic Acids Research] Scientists showed that β-Catenin was a substrate of lysine specific demethylase 1 (LSD1). Demethylation by LSD1 prevented β-Catenin degradation thereby maintaining its nuclear levels.
Dermal Cell News
An Anti-Oxidative and Active Shrinkage Hydrogel Integratedly Promotes Re-Epithelization and Skin Constriction for Enhancing Wound Closure
[Advanced Materials] The antioxidative active-shrinkage hydrogel relieved overactivated inflammation, prevented cellular apoptosis, and promoted fibroblast migration in vitro by reducing excessive reactive oxygen species.
Dermal Cell News
Macromolecular Crowding in Human Tenocyte and Skin Fibroblast Cultures: A Comparative Analysis
[Materials Today Bio] The authors compared human tenocyte and dermal fibroblast behavior under standard and macromolecular crowding conditions to inform future studies in tendon engineering.
Dermal Cell News
Green Cocoon-Derived Sericin Reduces Cellular Damage Caused by Radiation in Human Keratinocytes
[Scientific Reports] Researchers investigated the effects of green cocoon-derived sericin on human keratinocytes using lactate dehydrogenase activity to indicate damage reduction.
Dermal Cell News
Collagen I Protects Human Keratinocytes HaCaT against UVB Injury via Restoring PINK1/Parkin-Mediated Mitophagy
[Archives Of Biochemistry And Biophysics] Cells grown on plates coated by molecular collagen I, but not fibrillar collagen I, acquired certain resistance against UVB damages, as shown by increased survival and reduced apoptosis.
Dermal Cell News
ANKRD1 Is a Mesenchymal-Specific Driver of Cancer-Associated Fibroblast Activation Bridging Androgen Receptor Loss to AP-1 Activation
[Nature Communications] Investigators identified ANKRD1 as a mesenchymal-specific transcriptional coregulator under direct androgen receptor negative control in human dermal fibroblasts and a key driver of cancer-associated fibroblasts conversion, independent of cellular senescence.