Publication

[Arteriosclerosis Thrombosis And Vascular Biology] Thrombosis was induced by inferior vena cava stenosis through ligation in mice. After 1 day, a P-selectin-blocking antibody or isotype control was administered and thrombus composition and resolution were analyzed.

[Cell Stem Cell] The authors described an organoid culture method for cultivating patient-derived lymphoma organoids, which included cells from the native follicular lymphoma tumor microenvironment.

[Cancer Letters] Researchers explored organoid culture recipes to capture tumor features of colorectal cancers. They found that the activation of Wnt and EGF signaling and inhibition of BMP signaling were non-essential for the survival of most colorectal cancer organoids.

[Advanced Science] The transcriptomic and chromatin accessibility landscapes of matched colorectal cancer patient-derived organoids (PDO), patient-derived organoids xenografts (PDX), PDO-derived PDX, and original patient tumors were compared. Two major remodeling axes were discovered.

[Stem Cells] Human embryonic stem cell-derived chambered cardiac organoid was used as a model system to study the effects of mesenchymal stem cell (MSC)-derived small extracellular vesicles on myocardial ischemia-reperfusion injury (IRI).

[ACS Applied Materials & Interfaces] A type of direct breast cancer cells–tumor-associated macrophages coculture organoid model was well developed by a sequential culture method in this study. Alginate cryogels were fabricated with appropriate physical and mechanical properties to serve as an alternative extracellular matrix.