Publication

[Cell Reports] Using an ultrasensitive graphene oxide microfluidic chip nanotechnology built with graphene oxide sheets, researchers were able to demonstrate that circulating tumor cells could be specifically isolated and molecularly characterized to predict future progression in patients with stage III NSCLC.

[American Journal Of Respiratory And Critical Care Medicine] Single cell transcriptomics revealed an impaired interferon signaling and reduced expression of MHC I and II encoding genes in epithelial cells of cyctic fibrosis children at baseline, which was partially restored by elexacaftor/tezacaftor/ivacaftor.

[ACS Applied Materials & Interfaces] A new type of pH-responsive dual androgen-blocking nanodrug based on a molecularly imprinted polymer was designed and synthesized, and could selectively sequester testosterone from the prostate tumor.

[Cell Death & Disease] The authors discovered that CYLD inhibited tumor cell proliferation and enhanced the sensitivity to cell ferroptosis in prostate cancer in vitro and in vivo, respectively.

[Cancer Letters] Different cellular/molecular/preclinical approaches with human prostate cancer-samples, and in vitro/in-vivo prostate cancer-models were used to comprehensively characterize the RNA-Exosome-complex profile and explore its role in prostate cancer.

[Oncogene] SMYD2 knockdown dramatically inhibited the proliferation, migration, invasion, and epithelial-mesenchymal transition potential of 22Rv1 and C4-2 cells.