Publication

[Hypertension Research] The authors clarified the impact of chronic hypertension on obstetric hemorrhage by evaluating a nationwide administrative database in Japan. Women who gave birth between 2018 and 2022 were enrolled.

[Journal Of Translational Medicine] The authors investigated how physiological bone environments affect the osteogenic commitment of recalcitrant MSCs in vitro and in vivo. To this end, MSC of bone marrow and Wharton's jelly origin were co-cultured and induced for synchronous osteogenic differentiation in vitro using transwells.

[Cells & Development] Researchers established a model of mouse ESC differentiation and examined the dynamics of γH2AX foci during the process.

[Science Advances] The authors found that ESCs were depleted for H3K79me2 at shared locations of enrichment with somatic cells, which were highly and ubiquitously expressed housekeeping genes, and have lower RNA polymerase II at the transcription start site despite greater nascent transcription.

[Nucleic Acids Research] Researchers uncovered a highly dynamic and oscillatory pattern of translational reprogramming that contributes to the translational regulation of specific mRNAs with different modes of polysomal occupancy/translation that are important for oocyte and embryo developmental competence.

[Stem Cell Research] Investigators described the reprogramming of skin fibroblasts obtained from a healthy 59-year-old individual without Alzheimer’s disease.