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Dendritic Cell-Based In Situ Nanovaccine for Reprogramming Lipid Metabolism to Boost Tumor Immunotherapy

[ACS Nano] Scientists engineered an in situ nanovaccine based on lipid metabolism-regulating and innate immune-stimulated nanoparticles.

T Proliferating Cells Derived Autophagy Signature Associated with Prognosis and Immunotherapy Resistance in a Pan-Cancer Analysis

[iScience] Investigators manually curated an autophagy gene set and defined a pan-cancer autophagy signature by comparing malignant tissues and normal tissues in The Cancer Genome Atlas cohort.

Simvastatin Differentially Modulates Glial Functions in Cultured Cortical and Hypothalamic Astrocytes Derived from Interferon α/β Receptor Knockout Mice

[Neurochemical Research] The authors investigated the effects of simvastatin in inflammatory and functional parameters of primary cortical and hypothalamic astrocyte cultures obtained from IFNα/β receptor knockout mice.

CD62L Expression Marks a Functionally Distinct Subset of Memory B Cells

[Cell Reports] Researchers showed that CD62L and CD44 were progressively expressed on mouse memory B cells and identify transcriptionally and functionally distinct memory B cell subsets.

Cross-Talk Between Gastric Cancer and Hepatic Stellate Cells Promotes Invadopodia Formation During Liver Metastasis

[Cancer Science] Investigators found that the levels of invadopodia-associated proteins were significantly higher in liver metastasis than in the primary tumors of patients with gastric cancer with liver metastasis.

Evolution and Neutralization Escape of the SARS-CoV-2 BA.2.86 Subvariant

[Nature Communications] Researchers reported on the isolation of the live BA.2.86 subvariant from a diagnostic swab collected in South Africa which was tested for escape from neutralizing antibodies and viral replication properties in cell culture.

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