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Human Immunology News
Dendritic Cell-Based In Situ Nanovaccine for Reprogramming Lipid Metabolism to Boost Tumor Immunotherapy
[ACS Nano] Scientists engineered an in situ nanovaccine based on lipid metabolism-regulating and innate immune-stimulated nanoparticles.
Human Immunology News
T Proliferating Cells Derived Autophagy Signature Associated with Prognosis and Immunotherapy Resistance in a Pan-Cancer Analysis
[iScience] Investigators manually curated an autophagy gene set and defined a pan-cancer autophagy signature by comparing malignant tissues and normal tissues in The Cancer Genome Atlas cohort.
Neural Cell News
Simvastatin Differentially Modulates Glial Functions in Cultured Cortical and Hypothalamic Astrocytes Derived from Interferon α/β Receptor Knockout Mice
[Neurochemical Research] The authors investigated the effects of simvastatin in inflammatory and functional parameters of primary cortical and hypothalamic astrocyte cultures obtained from IFNα/β receptor knockout mice.
Immune Regulation News
CD62L Expression Marks a Functionally Distinct Subset of Memory B Cells
[Cell Reports] Researchers showed that CD62L and CD44 were progressively expressed on mouse memory B cells and identify transcriptionally and functionally distinct memory B cell subsets.
Hepatic Cell News
Cross-Talk Between Gastric Cancer and Hepatic Stellate Cells Promotes Invadopodia Formation During Liver Metastasis
[Cancer Science] Investigators found that the levels of invadopodia-associated proteins were significantly higher in liver metastasis than in the primary tumors of patients with gastric cancer with liver metastasis.
Immunology of Infectious Disease News
Evolution and Neutralization Escape of the SARS-CoV-2 BA.2.86 Subvariant
[Nature Communications] Researchers reported on the isolation of the live BA.2.86 subvariant from a diagnostic swab collected in South Africa which was tested for escape from neutralizing antibodies and viral replication properties in cell culture.