Publication

[Cancer Letters] The authors conducted scRNA-seq for paired primary tumors and organoids from one cholangiocarcinoma and two pancreatic ductal adenocarcinoma patients.

[Environmental Research] Investigators utilized brain organoids with optic vesicles to systematically analyze the neurotoxicity of arsenic and lead.

[Molecular Neurobiology] Scientists investigated the involvement of cystatin B in synaptic plasticity, using synaptosomes from human cerebral organoids as well as from rodents’ brain.

[Differentiation] Researchers described the stepwise and fully 3D production of hepatic organoids from hPSCs. They optimized every differentiation step by screening for optimal concentrations and timing of differentiation signals in each differentiation step.

[Biological Trace Element Research] The authors investigated the effects of boric acid on the expression of DNA double-strand break repair genes in breast CSCs, which has not been studied in the literature before.

[Cancer Gene Therapy] Scientists investigated the role and mechanism of long non-coding RNAs in regulating the interaction between melanoma CSCs and non-CSCs during the metastatic colonization process.