Publication

[Molecular Carcinogenesis] Using estrogen receptor positive breast cancer cell models, researchers showed that acquired resistance to abemaciclib was accompanied by increase in metastatic potential.

[Canadian Journal Of Physiology And Pharmacology] Scientists assessed the effect of restoring p53 using PRIMA-1 on the anti-cancer activity of olaparib against TP53-mutant TNBC cells and explored the optimum synergistic concentrations and the underlying mechanism.

[Scientific Reports] Using in vitro and in vivo models, investigators showed that GCNT1 promoted the growth of prostate tumors and could modify the glycome of prostate cancer cells.

[Molecular Biology Reports] Researchers evaluated the effects of betanin combined with radiation therapy as a potential radiosensitizing agent in the PC-3 cell line.

[Stem Cells Translational Medicine] PLXNB3 bound to and activated the MET receptor tyrosine kinase, leading to activation of the SRC non-receptor tyrosine kinase and subsequently focal adhesion kinase, which promotes cancer cell migration and invasion.

[Journal Of Molecular Medicine] The authors evaluated individual sphere proliferation and stemness toward chemotherapeutic treatment with doxorubicin and cisplatin in bladder cancer cell lines cultured in microfluidic devices used as CSC treatment response platform.