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Immune Evasion on the Nanoscale: Small Extracellular Vesicles in Pancreatic Ductal Adenocarcinoma Immunity

[Seminars In Cancer Biology] The authors summarize the present understanding on the crosstalk among tumour cells and the cellular immune microenvironment emphasizing the pro-malignant role played by extracellular vesicles in PDAC.

The Contribution of the AT1 Receptor to Erythropoiesis

[Biochemical Pharmacology] The authors present multiple evidence supporting that angiotensin II modulates physiological and pathological erythropoiesis processes trough the AT1 receptor.

The Evolving Views of Hematopoiesis: From Embryo to Adulthood and from In Vivo to In Vitro

[Journal Of Genetics And Genomics] Scientists review the evolving views of HSPC biology during developmental and postnatal hematopoiesis. Moreover, we discuss recent advances in the in vitro induction and expansion of HSPCs, with a focus on the implications for clinical applications.

Epithelial Specific Splicing Regulator Proteins as Emerging Oncogenes in Aggressive Prostate Cancer

[Oncogene] Scientists discuss how expression of the splicing regulators ESRP1 and ESRP2, and how their role as “masterminds” of epithelial splicing patterns, have been identified as markers of aggressively proliferating prostate primary tumors.

Membrane Organization by Tetraspanins and Galectins Shapes Lymphocyte Function

[Nature Reviews Immunology] Scientists advocate for a novel approach to study lymphocyte function by globally analysing the role of membrane organizers in the assembly of different membrane complexes, and discuss opportunities to develop therapeutic approaches that act via the modulation of membrane organization.

Versatile Roles of Innate Lymphoid Cells at the Mucosal Barrier: From Homeostasis to Pathological Inflammation

[Experimental & Molecular Medicine] The authors discuss recent advances regarding our understanding of the biology of innate lymphoid cells in mucosal tissue health and disease.

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