Tag results:
Review
Mammary Cell News
Functional Impact of Non-Coding RNAs in High-Grade Breast Carcinoma: Moving from Resistance to Clinical Applications: A Comprehensive Review
[Biochimica Et Biophysica Acta-Reviews On Cancer] The authors present a systematic overview of biogenesis and down streaming molecular mechanism of the subgroups of non-coding RNAs (ncRNAs). They also explain ncRNA-based strategies and challenges to target the chemo-, radio-, and immunoresistance in TNBCs from a clinical standpoint.
Extracellular Matrix News
Pulmonary Vascular Fibrosis in Pulmonary Hypertension – the Role of the Extracellular Matrix as a Therapeutic Target
[Pharmacology & Therapeutics] The complexity of the regulation of vascular fibrosis and stiffening in pulmonary hypertension allows the exploration of numerous potential therapeutic interventions.
Newsletters
The Placenta: Epigenetic Insights into Trophoblast Developmental Models of a Generation-Bridging Organ with Long-Lasting Impact on Lifelong Health
[Physiological Reviews] Scientists provide an overview of placental development and highlight the instructional role of the epigenome in dictating cell fate decisions specifically in the placental trophoblast cell lineage.
Immunology of Infectious Disease News
Pulmonary Fibrosis in COVID19: Mechanisms, Consequences, and Targets
[Qjm-An International Journal Of Medicine] Given the importance of pulmonary fibrosis irrespective of cause, understanding the similarities and differences in pathogenesis due to SARs-Cov2-induced pulmonary fibrosis may yield new therapeutic targets.
Human Immunology News
Microfluidic Organ-Chips and Stem Cell Models in the Fight against COVID-19
[Circulation Research] The authors discuss recent advancements in microfluidics, organ-on-a-chip, and human stem cell–derived models to study SARS-CoV-2 infection in the physiological organ microenvironment, together with their limitations.
Human Immunology News
Prostate Organoids: Emerging Experimental Tools for Translational Research
[Journal Of Clinical Investigation] Investigators discuss how prostate organoid technology is currently being used, the promising areas of future therapeutic applications, and the current obstacles to be overcome.