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Unlocking Ferroptosis in Prostate Cancer — the Road to Novel Therapies and Imaging Markers
[Nature Reviews Urology] The authors describe novel molecular underpinnings and metabolic drivers of ferroptosis, analyze the functions and mechanisms of ferroptosis in tumors, and highlight prostate cancer-specific susceptibilities to ferroptosis.
Immunology of Infectious Disease News
Biofabrication Directions in Recapitulating the Immune System-on-a-Chip
[Advanced Healthcare Materials] The authors cover the state of the art in the intricate landscape of immune organs-on-chip models, shedding light on the pivotal role of biofabrication technologies in bridging the gap between conceptual design and physiological relevance.
Neural Cell News
Neurofilaments as Biomarkers in Neurological Disorders — towards Clinical Application
[Nature Reviews Neurology] The authors summarize potential clinical applications of neurofilaments as a biomarker of neuro-axonal damage in a range of neurological disorders, including MS, Alzheimer's disease, frontotemporal dementia, ALS, traumatic brain injury, and Parkinson's disease.
Neural Cell News
Therapeutic Role of PTEN in Tissue Regeneration for Management of Neurological Disorders: Stem Cell Behaviors to an In-Depth Review
[Cell Death & Disease] The authors provide a comprehensive overview of the mechanisms by which phosphatase and tensin homolog deleted on chromosome 10 (PTEN) regulates activities of different stem cell populations and influences neurological disorders, encompassing autism, stroke, spinal cord injury, traumatic brain injury, Alzheimer’s disease, and Parkinson’s disease.
Muscle Cell News
MicroRNA-Mediated Regulation of Muscular Atrophy: Exploring Molecular Pathways and Therapeutics
[Molecular Medicine Reports] The authors lay a foundation for the development of novel treatment options for individuals affected by muscular atrophy, and explore other regulatory pathways, such as autophagy and inflammatory signaling.
Endothelial Cell News
Canonical and Non-Canonical Roles of Complement in Atherosclerosis
[Nature Reviews Cardiology] Scientists summarize the classical and the emerging non-classical roles of the complement system in the pathogenesis of atherosclerosis.