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The Conundrum of Helicobacter pylori-Associated Apoptosis in Gastric Cancer

[Trends in Cancer] Scientists address the conundrum of H. pylori-associated apoptosis and review distinct mechanisms induced in host cells that either promote or suppress apoptosis in gastric epithelial cells.

P38 Kinase in Gastrointestinal Cancers

[Cancer Gene Therapy] Investigators provide an overview of p38 and p38γ with respect to gastrointestinal cancers. Targeting p38γ is also discussed as a potential therapy for gastrointestinal cancers.

A 360° View of the Inflammasome: Mechanisms of Activation, Cell Death, and Diseases

[Cell] The authors present an overview of inflammasome pathways, outlining the mechanisms of inflammasome formation, subcellular regulation, and pyroptosis, and discuss the wide-reaching effects of inflammasomes in human disease.

Application of Mesenchymal Stem Cells (MSCs) in Neurodegenerative Disorders: History, Findings, and Prospective Challenges

[Pathology - Research and Practice] The authors compared and contrasted the numerous mesenchymal cell sources and their cellular features. These many sources of mesenchymal cells included adipocyte cells, fetal umbilical cord tissue, and bone marrow.

Vascularized Human Brain Organoid On-Chip

[Lab On A Chip] The authors elaborate on different strategies to improve the vascularized human brain organoid microenvironment using microfluidic devices, while discussing the current obstacles and future directions in this field.

Advances and Applications of Brain Organoids

[Neuroscience Bulletin] Scientists summarize recent advances in brain organoid technologies and their applications in brain development and diseases, including neurodevelopmental, neurodegenerative, psychiatric diseases, and brain tumors.

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