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Exosomes Derived from Mesenchymal Stem Cells in Diabetes and Diabetic Complications
[Cell Death & Disease] The authors outline the properties of mesenchymal stromal cell-derived exosomes, and provide a thorough summary of their biological functions and potential uses in diabetes and its related complications.
Extracellular Matrix News
Epigenetic Deregulation in Breast Cancer Microenvironment: Implications for Tumor Progression and Therapeutic Strategies
[Biomedicine & Pharmacotherapy] Scientists delve into the complex connections between breast cancer treatment response, underlying epigenetic changes, and vital interactions within the tumor microenvironment.
Mammary Cell News
CDK7 in Breast Cancer: Mechanisms of Action and Therapeutic Potential
[Cell Communication And Signaling] Scientists delineated the biological roles of CDK7 and explicates the molecular pathways through which CDK7 exacerbates the oncogenic progression of breast cancer.
Immune Regulation News
Organoids as a Tool to Study Homeostatic and Pathological Immune–Epithelial Interactions in the Gut
[Clinical & Experimental Immunology] Researchers provided an overview of how intestinal organoids are being co-cultured with immune cells leading to substantial advances in our understanding of immune–epithelial interactions in the gut.
Mammary Cell News
FGFR4-Driven Plasticity in Breast Cancer Progression and Resistance to Therapy
[British Journal Of Cancer] The authors summarize the role of FGFR4 in breast cancer, with a special focus on its contribution to subtype switching during metastatic spread and/or induced by therapy.
Hematopoiesis News
Role of Reactive Oxygen Species in Myelodysplastic Syndromes
[Cellular & Molecular Biology Letters] The authors review the eminent role of reactive oxygen species in the hematological niche and their profound influence on the progress of myelodysplastic syndromes.