The authors identified an important role for oncogenic ALK-ERK1/2-SP1 signaling in the maintenance of undifferentiated neural crest-derived progenitors through the repression of DLG2, a candidate tumor suppressor gene in neuroblastoma.
[Cell Reports]
6807162 6P96TME5 items 1 apa 0 default asc 1 154421 https://www.stemcellsciencenews.com/wp-content/plugins/zotpress/ %7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3A%22zotpress-d26c48180b4d3a5025e64f264e6ee844%22%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%226P96TME5%22%2C%22library%22%3A%7B%22id%22%3A6807162%7D%2C%22meta%22%3A%7B%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3E%3Ci%3E11q%20Deletion%20or%20ALK%20Activity%20Curbs%20DLG2%20Expression%20to%20Maintain%20an%20Undifferentiated%20State%20in%20Neuroblastoma%3A%20Cell%20Reports%3C%5C%2Fi%3E.%20%28n.d.%29.%20Retrieved%20September%2023%2C%202020%2C%20from%20%3Ca%20href%3D%27https%3A%5C%2F%5C%2Fwww.cell.com%5C%2Fcell-reports%5C%2Ffulltext%5C%2FS2211-1247%2820%2931160-8%27%3Ehttps%3A%5C%2F%5C%2Fwww.cell.com%5C%2Fcell-reports%5C%2Ffulltext%5C%2FS2211-1247%2820%2931160-8%3C%5C%2Fa%3E%20%3Ca%20title%3D%27Cite%20in%20RIS%20Format%27%20class%3D%27zp-CiteRIS%27%20href%3D%27https%3A%5C%2F%5C%2Fwww.stemcellsciencenews.com%5C%2Fwp-content%5C%2Fplugins%5C%2Fzotpress%5C%2Flib%5C%2Frequest%5C%2Frequest.cite.php%3Fapi_user_id%3D6807162%26amp%3Bitem_key%3D6P96TME5%27%3ECite%3C%5C%2Fa%3E%20%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22webpage%22%2C%22title%22%3A%2211q%20Deletion%20or%20ALK%20Activity%20Curbs%20DLG2%20Expression%20to%20Maintain%20an%20Undifferentiated%20State%20in%20Neuroblastoma%3A%20Cell%20Reports%22%2C%22creators%22%3A%5B%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.cell.com%5C%2Fcell-reports%5C%2Ffulltext%5C%2FS2211-1247%2820%2931160-8%22%2C%22language%22%3A%22%22%2C%22deleted%22%3A1%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222020-09-23T16%3A55%3A30Z%22%7D%7D%5D%7D11q Deletion or ALK Activity Curbs DLG2 Expression to Maintain an Undifferentiated State in Neuroblastoma: Cell Reports. (n.d.). Retrieved September 23, 2020, from
https://www.cell.com/cell-reports/fulltext/S2211-1247(20)31160-8 Cite