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Pulmonary Cell NewsInhibiting the excessive noradrenaline release by treatment with vitamin B6 supplementation into the brain and α2A adrenoreceptor agonist guanfacine (GFC) suppressed the increased NA metabolism and ameliorated the behavioral deficits.
[Translational Psychiatry]
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Toriumi, K., Miyashita, M., Suzuki, K., Yamasaki, N., Yasumura, M., Horiuchi, Y., Yoshikawa, A., Asakura, M., Usui, N., Itokawa, M., & Arai, M. (2021). Vitamin B6 deficiency hyperactivates the noradrenergic system, leading to social deficits and cognitive impairment. Translational Psychiatry, 11(1), 1–11. https://doi.org/10.1038/s41398-021-01381-z Cite
