Genetic Effects on Liver Chromatin Accessibility Identify Disease Regulatory Variants

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Researchers mapped caQTLs in human liver tissue in 20 liver samples and identified 3,123 caQTLs.
[The American Journal of Human Genetics]
Currin, K. W., Erdos, M. R., Narisu, N., Rai, V., Vadlamudi, S., Perrin, H. J., Idol, J. R., Yan, T., Albanus, R. D., Broadaway, K. A., Etheridge, A. S., Bonnycastle, L. L., Orchard, P., Didion, J. P., Chaudhry, A. S., Barnabas, B. B., Black, S., Bouffard, G. G., Brooks, S. Y., … Mohlke, K. L. (2021). Genetic effects on liver chromatin accessibility identify disease regulatory variants. The American Journal of Human Genetics, 0(0). https://doi.org/10.1016/j.ajhg.2021.05.001 Cite
Abstract