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Pulmonary Cell NewsTo investigate whether H3K27M was associated with distinct chromatin structure that altered transcription regulation, investigators generated the first high-resolution genome structure maps of pediatric high-grade gliomas cell lines and tumor tissue.
[Science Advances]
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Wang, J., Huang, T. Y.-T., Hou, Y., Bartom, E., Lu, X., Shilatifard, A., Yue, F., & Saratsis, A. (2021). Epigenomic landscape and 3D genome structure in pediatric high-grade glioma. Science Advances, 7(23), eabg4126. https://doi.org/10.1126/sciadv.abg4126 Cite
