Investigators suggested that nicotine has the potential to facilitate pancreatic fibrosis in chronic pancreatitis.
[Toxicology Letters]
7753456 {7753456:VEU8Q9PA} apa 50 1 163727 https://www.stemcellsciencenews.com/wp-content/plugins/zotpress/ %7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3A%22zotpress-da5a9c1cd31092db47e14dbe554fb91b%22%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22VEU8Q9PA%22%2C%22library%22%3A%7B%22id%22%3A7753456%7D%2C%22meta%22%3A%7B%22parsedDate%22%3A%222021-10-01%22%2C%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ENicotine%20facilitates%20pancreatic%20fibrosis%20by%20promoting%20activation%20of%20pancreatic%20stellate%20cells%20via%20%26%23x3B1%3B7nAChR-mediated%20JAK2%5C%2FSTAT3%20signaling%20pathway%20in%20rats.%20%282021%29.%20%3Ci%3EToxicology%20Letters%3C%5C%2Fi%3E%2C%20%3Ci%3E349%3C%5C%2Fi%3E%2C%2084%26%23x2013%3B91.%20%3Ca%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.toxlet.2021.06.012%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.toxlet.2021.06.012%3C%5C%2Fa%3E%20%3Ca%20title%3D%27Cite%20in%20RIS%20Format%27%20class%3D%27zp-CiteRIS%27%20href%3D%27https%3A%5C%2F%5C%2Fwww.stemcellsciencenews.com%5C%2Fwp-content%5C%2Fplugins%5C%2Fzotpress%5C%2Flib%5C%2Frequest%5C%2Frequest.cite.php%3Fapi_user_id%3D7753456%26amp%3Bitem_key%3DVEU8Q9PA%27%3ECite%3C%5C%2Fa%3E%20%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Nicotine%20facilitates%20pancreatic%20fibrosis%20by%20promoting%20activation%20of%20pancreatic%20stellate%20cells%20via%20%5Cu03b17nAChR-mediated%20JAK2%5C%2FSTAT3%20signaling%20pathway%20in%20rats%22%2C%22creators%22%3A%5B%5D%2C%22abstractNote%22%3A%22Smoking%20has%20been%20considered%20as%20a%20risk%20factor%20of%20chronic%20pancreatitis%20%28CP%29%2C%20but%20the%20potential%20mechanism%20is%20still%20unknown.%20The%20major%20pathological%20featur%5Cu2026%22%2C%22date%22%3A%222021%5C%2F10%5C%2F01%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.toxlet.2021.06.012%22%2C%22ISSN%22%3A%220378-4274%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.sciencedirect.com%5C%2Fscience%5C%2Farticle%5C%2Fabs%5C%2Fpii%5C%2FS0378427421001648%22%2C%22collections%22%3A%5B%223XSKJF5U%22%5D%2C%22dateModified%22%3A%222021-06-22T17%3A24%3A16Z%22%7D%7D%5D%7DNicotine facilitates pancreatic fibrosis by promoting activation of pancreatic stellate cells via α7nAChR-mediated JAK2/STAT3 signaling pathway in rats. (2021).
Toxicology Letters,
349, 84–91.
https://doi.org/10.1016/j.toxlet.2021.06.012 Cite 
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