SON Drives Oncogenic RNA Splicing in Glioblastoma by Regulating PTBP1/PTBP2 Switching and RBFOX2 Activity

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Scientists identified SON as a master regulator that activates PTBP1-mediated oncogenic splicing while suppressing RBFOX2-mediated non-oncogenic neuronal splicing in glioblastoma multiforme.
[Nature Communications]

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