Intravital Imaging Technology Guides FAK-Mediated Priming in Pancreatic Cancer Precision Medicine according to Merlin Status

Scientists visualized transient manipulation of focal adhesion kinase, which integrated bidirectional cell-environment signaling, using intravital fluorescence lifetime imaging microscopy of the FAK-based Förster resonance energy transfer biosensor in mouse and patient-derived pancreatic ductal adenocarcinoma models.