A Novel Brain-Permeant Chemotherapeutic Agent for the Treatment of Brain Metastasis in Triple-Negative Breast Cancer

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Scientists investigated the activity of QBS10072S in vitro with various cell lines including the human TNBC cell line MDA-MB-231 and its brain-tropic derivative MDA-MB-231-BR3, where QBS10072S was found to be preferentially toxic to TNBC cells.
[Molecular Cancer therapeutics]
AbstractGraphical Abstract