Lipid-Induced DRAM Recruits STOM to Lysosomes and Induces LMP to Promote Exosome Release from Hepatocytes in NAFLD

The authors revealed a damage-regulated autophagy modulator (DRAM)-mediated mechanism for exosome secretion and provided the foundation for plasma exosomes as a potential biomarker for nonalcoholic fatty liver disease (NAFLD).