C1GALT1 Expression Predicts a Favorable Prognosis and Suppresses Malignant Phenotypes via TrkA Signaling in Neuroblastoma

The authors provided the first evidence for the existence of GalNAc-type O-glycans on TrkA and altered O-glycan structures by core 1 β1,3-galactosyltransferase (C1GALT1) could regulate TrkA signaling in neuroblastoma cells.