[Scientific Reports] Human mesenchymal endometrium stem/stromal cells subjected to oxidative stress entered into premature senescence accompanied by persistent DNA damage, irreversible cell cycle arrest, increased expression of the cell cycle inhibitors cell hypertrophy, and enhanced β-galactosidase activity.

[International Journal of Stem Cells] Researchers investigated the role of miRNA-29a-3p (miR-29a-3p) in human bone marrow mesenchymal stem cells (hBMSCs), and its relationship with steroid-associated osteonecrosis.

[International Journal of Stem Cells] Scientists investigated the effect of a flavonoid, 3, 4’-dihydroxyflavone on osteogenic differentiation of equine adipose-derived stromal cells .

[Advanced Science] Investigators found that overexpression of farnesoid X receptor (FXR), a main receptor for bile acids, improved the retention and cardioprotection of adipose tissue-derived MSC administered by intramyocardial injection in mice with myocardial infarction.

[Frontiers in Immunology] Investigators look to cancer immunotherapy as a model for the challenges MSCs may face in obese environments.

[Apoptosis] H3K27me3 cooperated with LncRNA Tmem235 promoter DNA methylation to inhibit the expression of LncRNA Tmem235 and promoted the apoptosis of bone marrow MSCs.

[Acta Biomaterialia] Results indicated that human MSC-derived cartilage formed in hypoxic culture displayed a significantly reduced hypertrophy level than normoxic culture.

[Acta Histochemica] The authors investigated the impact of the miR-25–3p/integrin beta-3 (ITGB3) axis on the osteogenic differentiation of bone marrow MSCs from patients with osteoporosis.

[Neuroscience Letters] Scientists focused on the EMF exposed multi-potential BMSCs which differentiated and successfully implanted in the substantia nigra pars compacta of Parkinson's disease rat model.

[Singapore-MIT Alliance for Research and Technology] Researchers from the Critical Analytics For Manufacturing Personalized-Medicine have developed a new method of detecting adventitious microbial contamination in MSC cultures, ensuring the rapid and accurate testing of cell therapy products intended for use in patients.

[Annual Review of Medicine] Mutations in the genes encoding erythropoietin (EPO), EPO receptor, HIF-2α, prolyl hydroxylase domain protein 2, or von Hippel–Lindau protein caused familial erythrocytosis.

[BMC Neurology] Scientists reported a case of extramedullary relapse of acute myeloid leukemia in the brachial plexus of a 41-year-old woman treated with allogeneic hematopoietic stem cell transplantation.