[Science Advances] Researchers exploited the stereotyped hair follicle development to delineate the function of PADI4, an enzyme converting peptidylarginine to citrulline.

[Advances in Wound Care] Understanding the basic mechanisms and intricate crosstalk underlying selective autophagy may facilitate the development of comprehensive strategies and therapeutic targets for wound healing.

[PloS One] Researchers explored the regulatory function of disrupted cholesterol homeostasis in the functioning of hair follicle stem cells and the cycling of hair follicles.

[Nature Metabolism] The authors show that BDH2 is a key effector of inter-organelle Fe(II) redistribution and ferroptosis vulnerability during melanoma transition from a melanocytic to a mesenchymal-like phenotype.

[Biofabrication] Researchers explored the influence of viscosity on trilineage differentiation of human bone marrow-derived MSCs (hMSCs) was disclosed by three-dimensionally culturing hMSCs in viscous media.

[British Journal of Pharmacology] The authors reveal that MSCs in 3D spheroids exhibit reduced proliferation, enhanced stemness, and distinct metabolic adaptations, including increased glycolysis and altered nutrient metabolism.

[Proceedings of the National Academy of Sciences of the United States of America] High-dimensional immunostaining of murine mammary tumor progression revealed that mammary tissue macrophages were localized in the peritumoral stroma and associated with eosinophils, which were previously shown to facilitate antitumor T cell responses.

[Journal for Immunotherapy of Cancer] Mouse tumor models were used to assess the antitumor efficacy of aOX40-mIL2-Fc by tumor growth and survival, and toxicity by body weight loss, inflammatory cytokine production, and natural killer cell proliferation in the blood.

[Cancer Gene Therapy] Scientists synthesize contemporary findings on the molecular mechanisms by which lncRNAs influence major oncogenic cascades in NSCLC.

[Parse Biosciences] Helmholtz Munich and Parse Biosciences announced a strategic partnership to generate the world’s broadest lung disease perturbation atlas, powered by Parse Biosciences’ GigaLab platform.

[Advanced Science] Investigators developed 4-mercaptobenzoic acid (MPBA)-modified copper nanozymes (CuMPBA) to simultaneously combat bacterial infections and toxin-triggered immune overactivation.

[American Journal of Physiology-Lung Cellular and Molecular Physiology] Researchers sorted epithelial and endothelial cell populations based on their differential surface markers from normal and bronchopulmonary dysplasia human lungs.