Stretch Increases Alveolar Type 1 Cell Number in Fetal Lungs through ROCK-Yap/Taz Pathway

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By manipulating ROCK pathway, scientists demonstrated that stretch-induced Yap/Taz activation promoted alveolar differentiation towards alveolar epithelial type 1 phenotype via ROCK activity.
[American Journal of Physiology-Lung Cellular and Molecular Physiology]

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Abstract