Investigators reported that the frequencies of SCID repopulating cells were greatly decreased in cord blood CD34+ hematopoietic stem cells and hematopoietic progenitor cells upon ex vivo culture.
[Journal of Clinical Investigation]
6445218
{6445218:ME4YIZAD}
1
apa
50
default
1
166375
https://www.stemcellsciencenews.com/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22ME4YIZAD%22%2C%22library%22%3A%7B%22id%22%3A6445218%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Chen%20et%20al.%22%2C%22parsedDate%22%3A%222021-08-31%22%2C%22numChildren%22%3A3%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BChen%2C%20Y.%2C%20Fang%2C%20S.%2C%20Ding%2C%20Q.%2C%20Jiang%2C%20R.%2C%20He%2C%20J.%2C%20Wang%2C%20Q.%2C%20Jin%2C%20Y.%2C%20Huang%2C%20X.%2C%20Liu%2C%20S.%2C%20Capitano%2C%20M.%2C%20Trinh%2C%20T.%2C%20Teng%2C%20Y.%2C%20Meng%2C%20Q.%2C%20Wan%2C%20J.%2C%20Broxmeyer%2C%20H.%2C%20%26amp%3B%20Guo%2C%20B.%20%282021%29.%20ADGRG1%20enriches%20for%20functional%20human%20hematopoietic%20stem%20cells%20following%20ex%20vivo%20expansion-induced%20mitochondrial%20oxidative%20stress.%20%26lt%3Bi%26gt%3BThe%20Journal%20of%20Clinical%20Investigation%26lt%3B%5C%2Fi%26gt%3B.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1172%5C%2FJCI148329%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1172%5C%2FJCI148329%26lt%3B%5C%2Fa%26gt%3B%20%26lt%3Ba%20title%3D%26%23039%3BCite%20in%20RIS%20Format%26%23039%3B%20class%3D%26%23039%3Bzp-CiteRIS%26%23039%3B%20data-zp-cite%3D%26%23039%3Bapi_user_id%3D6445218%26amp%3Bitem_key%3DME4YIZAD%26%23039%3B%20href%3D%26%23039%3Bjavascript%3Avoid%280%29%3B%26%23039%3B%26gt%3BCite%26lt%3B%5C%2Fa%26gt%3B%20%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22ADGRG1%20enriches%20for%20functional%20human%20hematopoietic%20stem%20cells%20following%20ex%20vivo%20expansion-induced%20mitochondrial%20oxidative%20stress%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yandan%22%2C%22lastName%22%3A%22Chen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Shuyi%22%2C%22lastName%22%3A%22Fang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Qingwei%22%2C%22lastName%22%3A%22Ding%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Rongzhen%22%2C%22lastName%22%3A%22Jiang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jiefeng%22%2C%22lastName%22%3A%22He%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Qin%22%2C%22lastName%22%3A%22Wang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yuting%22%2C%22lastName%22%3A%22Jin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Xinxin%22%2C%22lastName%22%3A%22Huang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sheng%22%2C%22lastName%22%3A%22Liu%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Maegan%22%2C%22lastName%22%3A%22Capitano%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thao%22%2C%22lastName%22%3A%22Trinh%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yincheng%22%2C%22lastName%22%3A%22Teng%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Qingyou%22%2C%22lastName%22%3A%22Meng%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jun%22%2C%22lastName%22%3A%22Wan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Hal%22%2C%22lastName%22%3A%22Broxmeyer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Bin%22%2C%22lastName%22%3A%22Guo%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222021%5C%2F08%5C%2F31%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1172%5C%2FJCI148329%22%2C%22ISSN%22%3A%220021-9738%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.jci.org%5C%2Farticles%5C%2Fview%5C%2F148329%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222021-09-02T00%3A40%3A19Z%22%7D%7D%5D%7D
Chen, Y., Fang, S., Ding, Q., Jiang, R., He, J., Wang, Q., Jin, Y., Huang, X., Liu, S., Capitano, M., Trinh, T., Teng, Y., Meng, Q., Wan, J., Broxmeyer, H., & Guo, B. (2021). ADGRG1 enriches for functional human hematopoietic stem cells following ex vivo expansion-induced mitochondrial oxidative stress. The Journal of Clinical Investigation. https://doi.org/10.1172/JCI148329 Cite

Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News